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Ingredients

The running reference for the actives that do most of the work.

Edited by BeautyTalks Editors

Ingredients - The index

Vitamin C is worth using and impossible to store

The mechanism is well documented. The problem is that the molecule is unstable, and most of the argument you read online is about formulation, not biology.

BeautyTalks Editors - 1 min - 18 Jun 2026

The index

What to layer, what to leave a night between

ActiveWhat it actually doesUse itPairs withNot the same night
Glycolic acidAn alpha hydroxy acid that loosens the bonds between surface corneocytes.PM, 1-2x a week--
NiacinamideSupports barrier lipid synthesis and moderates sebum. One of the few actives that plays well with everything.AM or PM, daily--
RetinalA retinoid one conversion step from retinoic acid, so it works faster than retinol at similar tolerability.PM, 2x a week to startNiacinamideGlycolic acid
RetinolThe most studied over-the-counter retinoid; two conversion steps from retinoic acid.--Salicylic acid
Salicylic acidA beta hydroxy acid that is oil-soluble, so it works inside the pore rather than only on the surface.---
Vitamin CAn antioxidant that also inhibits pigment transfer; unstable in water at high pH.---
Ingredients - the ingredients desk - BeautyTalks